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Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates

Source PNAS 美国科学院院刊10d ago
Summary

Proceedings of the National Academy of Sciences, Volume 123, Issue 41, October 2026. <br/>SignificanceNiemann–Pick type C is a severe neurodegenerative disorde…

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Desk
Science
Region
Americas
Language
English
Item ID
science-7d1d84dc

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Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates · Meridian Globe